Brodifacoum: The Ultimate Rodent Killer – How It Works & Why It’s So Effective

2025-04-24

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Brodifacoum: The Ultimate Rodent Killer – How It Works & Why It’s So Effective

What is Brodifacoum?

Brodifacoum is a highly potent, second-generation anticoagulant rodenticide used to eliminate rats, mice, and other rodents. Known for its single-dose lethality, it is one of the most powerful rodent control solutions available today.

Widely used in agriculture, warehouses, urban pest control, and public health programs, Brodifacoum is especially effective against rodent populations resistant to older poisons like warfarin.


How Does Brodifacoum Work?

Brodifacoum kills rodents by disrupting their blood clotting system, leading to internal bleeding and organ failure. Here’s how it works:

  1. Blocks Vitamin K Recycling

    • Brodifacoum inhibits vitamin K epoxide reductase, an enzyme needed to produce clotting factors (II, VII, IX, X).

    • Without these, the rodent’s blood cannot clot, causing internal hemorrhaging.

  2. Delayed but Guaranteed Kill

    • Rats & mice die within 3–7 days after consuming even a small dose.

    • The slow action prevents bait shyness—rodents don’t associate death with the bait.

  3. Highly Effective Against Resistant Rodents

    • Unlike first-generation rodenticides (warfarin), Brodifacoum works in a single feeding, making it ideal for stubborn infestations.

Brodifacoum is a highly potent anticoagulant rodenticide used to control rats, mice, and other rodents. As a second-generation anticoagulant, it is known for its single-dose lethality, meaning rodents only need to consume a small amount for it to be effective. It is widely used in professional pest control and is often found in commercial-grade rodenticides. Brodifacoum is also used in public health and agricultural settings due to its long-lasting effect, making it a powerful choice in situations where rodent resistance to older poisons has developed. How Does Brodifacoum Work? (Mechanism of Action) Brodifacoum’s mechanism of action involves inhibiting the enzyme vitamin K epoxide reductase, which is critical for the synthesis of blood clotting factors (II, VII, IX, and X). Without these, the rodent’s blood loses its ability to clot, leading to internal bleeding, organ failure, and eventual death. Brodifacoum: How Does It Work? Disrupts blood clotting by depleting vitamin K in the body. Causes internal hemorrhaging over time. Works after a single feeding in most cases. Death occurs without causing immediate pain, so the rodent doesn’t associate the poison with the bait. How Long Does Brodifacoum Take to Kill Rodents? How Long Does Brodifacoum Take to Kill Mice and Rats? Mice: Typically die within 3–5 days after ingestion. Rats: Usually die within 4–7 days, depending on size and health. This delayed action is strategic—it allows the rodents to return to their nests and not associate symptoms with the bait, reducing the risk of bait shyness and improving the effectiveness of control efforts.

What Does Brodifacoum Do to Rats and Mice? Induces gradual internal bleeding. Leads to lethargy, loss of appetite, and ultimately death. Death occurs internally and silently, often inside nests or burrows. Due to its potency, Brodifacoum is extremely effective even against resistant rodent populations that may have survived first-generation rodenticides like warfarin. Does Brodifacoum Kill Other Animals Like Squirrels? Does Brodifacoum Kill Squirrels? Yes, Brodifacoum can kill squirrels if ingested, as it affects all mammals in a similar way. However: Squirrels are not usually the target, and using Brodifacoum against them may violate local wildlife laws. Secondary poisoning of pets or wildlife (e.g., hawks, owls, cats) that eat poisoned rodents is a serious concern. For this reason, Brodifacoum use should follow strict safety guidelines to avoid harming non-target animals. Which Rodenticides Contain Brodifacoum? Brodifacoum is used globally in numerous professional and consumer-grade rodenticide brands. While we do not list product-specific names here, several well-known rodent control brands across North America, Europe, and Asia formulate their baits using Brodifacoum due to its proven efficacy. It is commonly found in the form of: Pest control professionals Farm and warehouse operators Municipal vector control departments Household users (in regulated packaging) Where to Buy Brodifacoum-Based Rodenticides? Retail Purchase: For retail consumers, Brodifacoum rodenticides may be available through: Licensed agricultural supply stores Pest control product retailers Home and hardware stores (where regulation allows) Online pest control suppliers (with legal restrictions in some countries) Note: In certain jurisdictions, Brodifacoum products may be restricted to licensed professionals. Wholesale Supply from a Reliable Manufacturer – Let’s Work Together We are a professional rodenticide and pesticide manufacturer and global exporter specializing in the bulk supply of Brodifacoum-based rodenticides. With over 10 years of experience in pest control solutions, our company offers: Custom formulations: Brodifacoum 0.005% in blocks, pellets, paste, or grain OEM and ODM services: Packaging, labeling, and branding according to client requirements Free samples for evaluation Regulatory support, including COA, MSDS, TDS, and registration dossiers Flexible minimum order quantities and door-to-door logistics solutions Our production facilities are ISO-certified, and every batch is tested for active ingredient content, moisture, stability, and performance under simulated storage conditions.

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